How Jamie-Lynn Sigler and Christina Applegate Are “Helping Each Other Through” Multiple Sclerosis: “We Both Needed This”

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Finding Strength in Friendship: Christina Applegate and Jamie-Lynn Sigler Open Up About Living with Multiple Sclerosis

Christina Applegate, known for her roles in popular TV shows like “Dead to Me,” and Jamie-Lynn Sigler, famous for her role in “The Sopranos,” have something more in common than just their successful acting careers. Both have been diagnosed with multiple sclerosis (MS), a chronic illness that affects the nervous system.

Their journey with MS began at different points in their lives. Applegate received her diagnosis in 2021 while filming her Netflix series, while Sigler’s diagnosis dates back more than two decades. Despite the challenges they face, they found solace and strength in their friendship, which was facilitated by a mutual friend, Lance Bass, after Applegate’s diagnosis.

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Now, the two actresses are using their platform to raise awareness about MS through their upcoming podcast called “MeSsy.” Scheduled to debut on March 19, the podcast will feature candid conversations with friends and former co-stars, including Martin Short and Edie Falco.

In “MeSsy,” Applegate and Sigler delve into various aspects of living with MS, from the physical symptoms like pain and mobility issues to the emotional toll it takes on their lives and relationships. They share personal anecdotes about parenting with MS, the challenges of accepting help, and the impact the disease has had on their careers.

Despite the difficulties, Applegate and Sigler approach their journey with MS with humor and honesty. They acknowledge the unpredictability of the disease while emphasizing the importance of staying hopeful and resilient. Their podcast isn’t just about MS; it’s about facing life’s challenges head-on, finding humor in adversity, and supporting each other through it all.

Through their podcast and public appearances, Applegate and Sigler aim to destigmatize MS and encourage others facing chronic illnesses to find strength in community and laughter. Their friendship serves as an inspiration to many, reminding us that even in the face of adversity, there is power in connection and resilience.

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